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CASE REPORT
Year : 2021  |  Volume : 12  |  Issue : 2  |  Page : 108-111

Oral submucous fibrosis: A case report and contemporary review of pathogenesis


1 PG Student, Department of Oral Pathology and Microbiology, SRM Dental College, SRMIST, Chennai, India
2 CRRI, Department of Oral Pathology and Microbiology, SRM Dental College, SRMIST, Chennai, India
3 Senior Lecturer, Department of Oral Pathology and Microbiology, SRM Dental College, SRMIST, Chennai, India

Correspondence Address:
Dr. V Vasanthi
Department of Oral Pathology and Microbiology, SRMIST, SRM Dental College, Ramapuram, Chennai - 600 089, Tamil Nadu
India
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DOI: 10.4103/srmjrds.srmjrds_18_21

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Oral submucous fibrosis (OSF) is an oral potentially malignant disorder characterized by fibroelastic changes in the juxta-epithelial layer leading to trismus. Areca nut and its metabolites contribute to the etiopathogenesis. We report a case of a 53-year-old male patient with burning sensation and reduced mouth opening. Clinical findings and histopathologic findings were consistent with the diagnosis of OSF – intermediate stage. The patient was conservatively managed with lycopene 4 mg twice daily for 3 months and also advised oral physiotherapy. The patient was educated on the effects of areca nut and chances of malignant transformation.


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